On May 16, 2025, U.Today reported that a substantial Bitcoin sell wall of $18,344,996,366 is acting as a barrier, preventing Bitcoin from rebounding to its all-time high.

On May 16, 2025, Coinsilium Group, a UK-based company, announced a £1.25 million raise to establish a Bitcoin treasury initiative, mirroring similar moves by Strategy, Metaplanet, and the U.S. Government; trading volume of Coinsilium Group shares reached a record 14 million on Friday, with shares trading at £0.04, a 24% increase over the past 24 hours; CoinDesk analyst James Van Straten aims to educate the UK market on Bitcoin following this announcement.

On May 16, 2025, Hong Kong-based Top Win International announced its rebranding to AsiaStrategy and a shift to managing its treasury in digital assets, partnering with Sora, a crypto-backed venture capital firm; the company's shares initially surged by 45% before declining to $5.14, a 31% decrease.

Published on May 16, 2025, Bitcoin had increased by approximately 60% over the past year and 10% over the last month as of May 15, 2025; Todd Rosenbluth from VettaFi suggests considering ETFs like the Calamos Bitcoin 80 Series Structured Alt Protection ETF (CBTJ) to manage risk.

On May 17, 2025, the ETH/BTC price ratio rebounded 38% from its weakest level since January 2020, suggesting investors and traders are betting the bottom is in and an "alt season" could soon follow; March Zheng, General Partner of Bizantine Capital, stated that ETH has typically been the main on-chain altcoin indicator for risk-on, and its sizable upticks generally lead to broader altcoin rallies; ETH spot trading volume relative to BTC surged to 0.89 last week, its highest since August 2024, signaling renewed appetite from investors.

On May 16, 2025, an article discussed a "Mind-Blowing $3,400,000,000 Bitcoin and Ethereum Expiry" and its potential impact on the market.

On May 16, 2025, crypto mining and data center firms experienced gains due to optimism about AI computing demand, spurred by CoreWeave's $4 billion deal with OpenAI; Bitcoin held just above $104,000, up 1.3% over the 24 hours.

On May 16, 2025, Galaxy Digital's shares commenced trading on the Nasdaq, celebrated by founder Mike Novogratz ringing the opening bell, with GLXY shares initially trading around $22.61, marking a 3.2% increase for the day.

On May 17, 2025, CryptoQuant reported that Ethereum (ETH) is undervalued compared to Bitcoin (BTC), with its trading level mirroring 2019 conditions, suggesting a potential rally; CryptoQuant's report indicated that ETH's ETH/BTC Market Value to Realized Value (MVRV) metric shows it is deeply undervalued compared to Bitcoin (BTC), a ratio not seen since 2019.

On May 17, 2025, it was reported that institutional investors are increasing their ETH holdings, anticipating it will outperform BTC, potentially due to the recent Pectra upgrade; demand for the ETH ETF has sharply picked up, with the ETH/BTC ETF holdings ratio rising steeply since late April, according to data from CryptoQuant, suggesting institutional investors anticipate ETH will outperform BTC.

As of May 16, 2025, fast food chain Steak n' Shake has started accepting Bitcoin payments through the Lightning network, following their announcement a week earlier.

On May 16, 2025, U.Today reported that Bitcoin (BTC) might be on the verge of experiencing a mini-Golden Cross.