49ers to play Cardinals in season finale; 49ers eliminated from playoffs; key players sidelined due to injuries
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- 49ers to face Cardinals in season finale: The San Francisco 49ers will play against the Arizona Cardinals on January 7, 2025, in Week 18 of the 2024 NFL season. The 49ers have been eliminated from playoff contention and will be missing key players due to injuries as they aim to finish the year strong.
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