On April 16, 2025, Israeli Prime Minister Benjamin Netanyahu ordered his negotiating team to continue efforts to secure the release of hostages held by Hamas in the Gaza Strip, following the end of a ceasefire and the resumption of Israeli ground operations. Netanyahu held a meeting with his negotiating team and security officials.

On April 16, 2025, Ukraine’s parliament voted to extend martial law and military mobilisation for another three months, prolonging the wartime measures until at least August 6. The extension of martial law passed by a 357-1 vote, while troop mobilisation was approved 356-1.

On April 16, 2025, United States President Donald Trump’s special envoy, Steve Witkoff, following a meeting with Russia’s President Vladimir Putin, said the latter was open to a “permanent peace” deal with Ukraine.

On April 16, 2025, Rafael Grossi stated that while Iran possesses enough material to produce several bombs, it does not yet have nuclear weapons, but is close. Grossi stated that Iran is “not far” from possessing a nuclear bomb, noting they have the pieces to assemble one.

Reported on April 16, 2025, Iran confirmed that the next round of nuclear talks with the US will be held in Rome on April 19, 2025. Oman will mediate the talks.

On April 16, 2025, Congolese officials reported that at least 50 people died after a boat caught fire in northwest DRC.

On April 16, 2025, amidst the 38th month of war, an overnight Russian drone attack on Odesa injured three and damaged homes, while attacks killed at least one in Kherson, according to Ukrainian officials. Kyiv’s air force said Moscow attacked Ukraine with 52 drones and one missile overnight, out of which 26 drones were shot down.

On April 16, 2025, Israel's Defence Minister Israel Katz announced that Israeli troops will remain indefinitely in Gaza, Lebanon, and Syria to act as a buffer between Israeli communities and the enemy.

Published on April 16, 2025, Amande Bazerolle, MSF’s emergency coordinator in the enclave, said on Wednesday, that Gaza has been turned into a mass grave of Palestinians and those coming to their assistance, as Israel’s continued bombardment of the Gaza Strip shows a “blatant disregard” for the safety of humanitarian workers.

On April 16, 2025, hundreds of Palestinians protested against Hamas in Gaza, calling for an end to the war with Israel, chanting slogans such as "Hamas out".

On April 16, 2025, the Russian military claimed its forces captured Kalynove in the Donetsk region and accused Ukraine of six attacks on Russia’s energy infrastructure, despite a mutually-agreed moratorium. The ministry also accused Kyiv of carrying out six attacks on Kremlin energy infrastructure in the past day, despite a mutually agreed 30-day moratorium on energy strikes.

On April 16, 2025, Ukraine’s military said it hit a base of the Russian rocket brigade which carried out the deadly missile attack that killed 35 people in Sumy city on Sunday.

On April 16, 2025, Al-Shabab fighters attacked Adan Yabaal, a strategic town in central Somalia. While Al-Shabab claimed control, the Somali army stated they pushed back the group.

Published on April 16, 2025, Defence Minister Israel Katz said on Wednesday that Israel’s “policy is clear and no humanitarian aid will be allowed into Gaza” as it is “one of the main pressure tools” against Hamas.

On April 16, 2025, a Russian military court jailed a Kremlin soldier for 15 years after convicting him of desertion and voluntarily surrendering to Ukraine. A Russian court also jailed five young Russian citizens, all in their 20s, for setting fire to a helicopter and railway equipment on behalf of Ukraine, handing them sentences of up to 18 years in prison.

On April 16, 2025, it was reported that observers from the Organization of American States (OAS) and the European Union (EU) rejected allegations of electoral fraud in the Ecuadorian presidential election on April 15.

On April 16, 2025, Iran’s Foreign Minister Abbas Araghchi warned the US about contradictory stances in the talks, following comments from US Middle East envoy Steve Witkoff. Araghchi emphasized that losing the right to enrich uranium is "non-negotiable."

On April 16, 2025, the British Foreign Secretary will meet with Steve Witkoff and Marco Rubio in Paris. This marks the first high-level exchange between the UK/France-led coalition and the White House since visits to Washington by Keir Starmer and Emmanuel Macron in February.

On April 18, 2025, French President Emmanuel Macron will receive US Secretary of State Marco Rubio and special envoy for the Middle East Steve Witkoff in Paris to discuss the war in Ukraine. Witkoff recently met with Vladimir Putin.

On April 16, 2025, Rafael Grossi, Director General of the IAEA, planned a visit to Iran and expressed his desire for the IAEA's involvement in any future agreement on Iran's nuclear program. He arrived in Tehran for talks that could include negotiations over the access of International Atomic Energy Agency (IAEA) inspectors.

On April 16, 2025, Iran’s President Masoud Pezeshkian formally approved the resignation of his vice president, who was Tehran’s key negotiator in the 2015 nuclear deal.

Reported on April 16, 2025, US President Donald Trump called Oman’s Sultan Haitham bin Tariq on April 15, 2025 while the ruler was on a trip to the Netherlands.

Reported on April 16, 2025, Grossi is scheduled to meet with President Pezeshkian and others in Tehran on April 17, 2025.

On April 16, 2025, Russian Foreign Minister Sergey Lavrov said in an interview with the Kommersant newspaper that it was not easy to agree with the US on “key components” of a possible peace deal to end the war in Ukraine.

On April 16, 2025, it was reported that Ukraine's constitution prevents elections during martial law, despite calls from Russia and the United States for a timeline on a future vote. Vladimir Putin has questioned Volodymyr Zelenskyy's legitimacy, whose term was originally due to end in May last year.

On April 16, 2025, a federal judge in Washington ruled that the Trump administration's expulsions of immigrants based on the 1798 Alien Enemies Act were in contempt of court. The judge had previously issued a temporary restraining order halting the expulsions.

On April 16, 2025, a US commander stated that the Pacific is threatened by cooperation between China, North Korea, and Russia.

On April 15, 2025, former US President Joe Biden delivered a speech in Chicago, Illinois, defending retirement aid and criticizing President Donald Trump’s policies. The speech was reported on April 16, 2025.

On April 15, 2025, the Social Security Administration (SSA) responded to Biden’s claims, accusing him of “lying” about the agency’s reform efforts in a post on X, as reported on April 16, 2025. Members of the DOGE team have been auditing the SSA agency, which Musk has criticized, planning to cut at least 7,000 staff and close down offices.

Published on April 16, 2025, Slovakia's Fico insists on attending Moscow's 'Victory Day' parade despite EU warnings.

On April 16, 2025, the World Health Organization (WHO) announced that its members have reached a landmark agreement on how to respond to future pandemics after more than three years of negotiations.

Published on April 17, 2025, glaciers in Sweden and Norway are melting faster.

On April 16, 2025, the UK Supreme Court ruled that the legal definition of a woman is based on biological sex, not gender, potentially impacting transgender women in the UK.