On March 28, 2025, US Vice-President JD Vance visited Greenland's Pituffik space base, advocating for US control to counter China and Russia and criticizing Denmark's handling. On March 29, 2025, Danish Foreign Minister Lars Lokke Rasmussen criticized the Trump administration, leading to protests in Copenhagen and increased Danish investment in Arctic defense ($2.1 billion).

On March 28, 2025, President Trump and Canadian Prime Minister Mark Carney discussed the ongoing trade war, with Trump calling the call "extremely productive." However, Carney stated Canada would implement retaliatory tariffs, noting the U.S. is no longer a reliable partner.

President Trump ramped up his trade war this week by announcing a 25% tariff on automobile imports from Canada, which are Canada’s second-largest export. Vice President JD Vance said Canada is threatening retaliatory tariffs and claimed that Canada has forced American farmers and manufacturers to play by an unfair set of rules for decades. Trump and Carney agreed that Dominic LeBlanc, Canada’s minister of international trade, and U.S. Secretary of Commerce Howard Lutnick will intensify talks to address the coming tariffs in the interim; all reported on March 28, 2025.

On March 28, 2025, the US ordered expanded screening for student visa applicants, including social media checks. The aim is to exclude those deemed to support terrorism.

On March 28, 2025, President Trump signed an executive order to eliminate collective bargaining for hundreds of thousands of federal workers. Union leaders have responded with accusations of union-busting.

On March 29, 2025, Columbia University's interim president, Katrina Armstrong, resigned and Claire Shipman was appointed acting president, after the Trump administration demanded policy changes in exchange for restoring $400 million in government funding. The Trump administration also initiated deportation proceedings against several students involved in pro-Palestinian demonstrations at Columbia University, including two lawful U.S. residents.

On March 28, 2025, it was reported that the Trump Administration is making final cuts to USAID. This effectively moves to eliminate the agency.

On March 28, 2025, the Trump administration announced that the U.S. Naval Academy changed its admissions policy to no longer consider race. This follows the Supreme Court's rejection of affirmative action in college admissions nearly two years prior.

On March 28, 2025, Health Secretary Robert F Kennedy Jr announced layoffs of nearly 20,000 workers at the Department of Health and Human Services (HHS). Senator Patty Murray criticized the cuts.

On March 29, 2025, healthcare agencies in Southern California expressed concerns that potential cuts to the CDC’s Division of HIV Prevention by the Trump administration could endanger lives and increase long-term costs. On March 27, 2025, the Department of Health and Human Services announced sweeping cuts in several federal health agencies, which have helped drive down the incidence of HIV.

On March 28, 2025, Utah became the first state to ban fluoride in public drinking water. This decision was made despite opposition from dentists and national health organizations.

The Trump administration ended funding for a study designed to protect pregnant women from domestic violence. The study was apparently labeled a "DEI study," and the defunding was reported on March 29, 2025.

The Wisconsin Supreme Court race between Susan Crawford and Brad Schimel has been significantly influenced by Elon Musk's financial involvement (over $20 million), making it the most expensive judicial election in US history. The election has drawn significant spending, totaling $90 million, due to its implications for abortion rights, redistricting, and labor rights. Donald Trump hosted a conference call to support Brad Schimel's campaign, while Susan Crawford has centered her campaign against Elon Musk's involvement, branding her statewide tour as "The People v. Elon Musk".

On March 29, 2025, a group of senators visited Guantanamo Bay, Cuba, where the Trump administration has been detaining migrants for deportation, criticizing the operation as "misguided". As of that Friday, 87 migrants, mostly from Latin America, were held at the facility, with 42 classified as "low risk".

On March 28, 2025, U.S. Secretary of Homeland Security, Kristi Noem, met with Mexican President Claudia Sheinbaum. Noem stated that while Mexico has made progress in security and migration, there is still much work to be done.

On March 29, 2025, California Governor Gavin Newsom stated that the Democratic brand is "toxic" during an appearance on "Real Time With Bill Maher". He criticized Democrats for various issues and cited a low favorability rating.

On March 29, 2025, San Diego is on the path to potentially becoming the first city in the U.S. to ban grocery stores from offering digital-only coupons. The ban aims to ensure that grocery stores provide paper coupons to all customers, including elderly shoppers, citing unequal access to the internet and smartphones.

On March 28, 2025, Jenner & Block and WilmerHale sued the Trump administration to block executive orders halting their government business and revoking attorney security clearances, arguing it's an unconstitutional attack. Skadden, Arps, Slate, Meagher & Flom reached a deal to avoid an executive order by performing $100m in pro-bono work. Paul Weiss also made a deal after facing an "existential crisis", while Perkins Coie successfully challenged an order.

On March 28, 2025, a federal judge temporarily blocked Donald Trump’s administration from shutting down Voice of America, preventing the firing of 1,300 employees. The judge ruled that the administration couldn't unilaterally terminate Voice of America and related programs without congressional approval.

On March 28, 2025, President Trump ordered a restructuring of the Smithsonian Institution to eliminate what his administration considers "improper, divisive, or anti-American ideology." This move has sparked criticism over potentially removing diversity from American history.

On March 28, 2025, former FTC commissioner Alvaro Bedoya, following his firing by President Trump, warned of a battle between "the rule of law versus the rule of billionaires". He cited concerns about backroom dealmaking within the Trump administration.

On March 28, 2025, Hillary Clinton criticized the Trump administration's approach to governing, calling it both dumb and dangerous. She predicted it would leave the US "feeble and friendless".

On March 27, 2025, during a Women's History Month event at the White House, Donald Trump referred to himself as "the fertilization president" while discussing an executive order aimed at expanding access to IVF. The event was published on March 29, 2025.

On March 28, 2025, Utah became the first state to prohibit flying LGBTQ+ pride flags at schools and all government buildings, with fines for violations starting May 7. Local leaders in Salt Lake City have illuminated the Salt Lake City and County Building in rainbow lights to protest the flag ban.