On 2025-03-22, reports indicated President Trump is expected to ban or severely restrict travel to the United States from more than a dozen countries, including Iran and Venezuela. The travel bans could affect 11 countries, and visa restrictions may be sharply imposed on 10 others. The State Department acknowledged it was reviewing all visa programs as mandated by Trump’s order.

On 2025-03-22, federal authorities arrested Mahmoud Khalil, a pro-Palestinian activist attending graduate school at Columbia University. Senator Rubio stated that visas and green cards of Hamas supporters in America would be revoked for deportation.

Venezuela agreed to resume accepting U.S. deportation flights, potentially starting on 2025-03-23, after initially suspending cooperation. Nicolás Maduro's prior suspension of deportation cooperation stemmed from the Trump administration revoking a policy that allowed increased Venezuelan oil production and export. Venezuela's agreement may be partly due to the Trump administration's recent deportation of Venezuelan migrants to El Salvador.

On 2025-03-22, it was reported that the Trump administration deported a kidney doctor with a work visa after she attempted to enter the country on a flight to Boston this month.

A draft agreement between the IRS and ICE, detailing the IRS's role in verifying addresses of individuals ordered for deportation, has been reported. The Trump administration replaced the top IRS lawyer, and the current information-sharing agreement under discussion with ICE is reportedly narrower than previous requests. The Department of Homeland Security's repeated attempts to involve IRS agents in immigration enforcement through company audits have been reported.

On 2025-03-22, reports indicate the Trump administration is reshaping FEMA by implementing a new hiring process that affects contract renewals, requiring DHS approval. This follows President Trump's executive order directing state and local governments to play a more active role in preparing for emergencies. DHS Secretary Kristi Noem supports the President's desire to reshape FEMA.

On 2025-03-21, Radio Free Asia furloughed most of its Washington staff. On 2025-03-22, Defense Secretary Pete Hegseth eliminated the Office of Net Assessment at the Pentagon, and the Cyber Safety Review Board was dissolved at the Department of Homeland Security. As the Voice of America was being dismantled, The Global Times commented that the VOA has been discarded by its own government. Mr. Trump's choice to head the global media agency, L. Brent Bozell III, has picked Kari Lake as the new head of Voice of America; however, she is currently only a "special adviser."

On 2025-03-22, Amy Gleason stated that the Department of Government Efficiency (DOGE) will continue as a permanent fixture within the White House. Jeremy Lewin stated he would be taking over operations at the U.S. Agency for International Development. Noah Peters, a DOGE staffer, has been ordered to be deposed about his team’s role in directing agencies to fire their probationary workers.

Published on 2025-03-23, Jessica Aber, former U.S. Attorney for the Eastern District of Virginia, was found dead on 2025-03-22 in Alexandria, Virginia. The cause of death is pending.

Published on 2025-03-22, President Trump's attempts to quickly resolve global conflicts in Gaza, Ukraine, and Iran have faced challenges. These include a collapsed cease-fire in Gaza, a rejected cease-fire proposal in Ukraine, and an elusive Iran nuclear agreement.

As of 2025-03-22, Perkins Coie sued President Trump in federal court and obtained a temporary restraining order against him. The showdown between a federal judge in Washington and the Trump administration continues over the president’s use of the Alien Enemies Act regarding Venezuelan migrants. On 2025-03-22, Keker, Van Nest & Peters called Mr. Trump’s latest memorandum “inexcusable and despicable.” On 2025-03-22, it was reported that President Trump attacked Marc Elias, blaming him for a dossier of unsubstantiated allegations about his links to Russia.

On 2025-03-22, it was reported that Elon Musk, a White House aide, is investing millions in pro-Trump causes for the April 1 election. Elon Musk also showed interest in the Wisconsin court election eight days after Tesla filed a lawsuit in January challenging Wisconsin’s law prohibiting vehicle manufacturers from owning dealerships.