In a Time magazine interview published on April 25, 2025, President Trump said that “Crimea will stay with Russia,” pressuring Ukraine to make concessions to end the war.

Trump envoy Steve Witkoff met with Putin in Moscow on April 25, 2025, marking their second meeting this month and the fourth since February.

On 2025-04-25, Donald Trump is set to attend Pope Francis’s funeral on April 26, 2025, in the Vatican’s St. Peter’s Square. This presents a diplomatic challenge due to Trump's strained relationships with international leaders and policies. It remains unclear if Trump and Zelensky, who also plan to attend, will meet separately.

On April 25, 2025, Attorney General Pam Bondi announced the Justice Department may once again seek reporters’ phone records and compel their testimony in leak investigations, reversing a Biden administration policy. This change is to safeguard a broader set of government secrets, according to an internal Justice Department memo from Ms. Bondi. This followed multiple criminal referrals to the Justice Department related to alleged leaks in the intelligence community by Director of National Intelligence Tulsi Gabbard, and occurred amidst escalating attacks on the US media by Donald Trump.

On 2025-04-25, President Trump stated that if the US fails to reach a nuclear deal with Iran, he would lead a military action against Iran, during an interview with Time magazine.

As of 2025-04-25, the IMF and World Bank spring meetings took place in Washington amid uncertainty caused by the Trump administration's chaotic tariffs. Policymakers reacted with "stunned resignation," and the IMF warned of potential economic shocks.

On 2025-04-25 (following rulings on 2025-04-24), the US government under President Donald Trump faced court setbacks regarding immigration, election, and anti-DEI policies. These included rulings against suppressing DEI programs, partially blocking an executive order on elections, and challenges to deportation policies and a ban on transgender people in the military.

On 2025-04-25, former U.S. Representative George Santos was sentenced to more than seven years in prison for federal wire fraud and aggravated identity theft.

On April 25, 2025, FBI agents arrested Milwaukee County Circuit Judge Hannah Dugan for allegedly obstructing immigration officials. She is accused of helping Eduardo Flores Ruiz, sought by immigration authorities, evade arrest in her courthouse and was charged with obstruction and concealing an individual to prevent arrest.

On April 25, 2025, a judge blocked the Trump administration from nixing collective bargaining for most federal employees.

On 2025-04-25, the Los Angeles city attorney’s office announced it would not file criminal charges against most protesters arrested at UCLA and USC during demonstrations over the war in Gaza in April and May 2024. Only two people will be charged out of over 300 referrals.

As of April 26, 2025, Canadians are canceling trips to the US due to President Trump's rhetoric and policies. There was a decrease of over 910,000 land crossings from Canada to the US last month compared to March 2024 (a decrease of over 22%), and Air Canada reported a decrease of about 10% in flight bookings from Canada to the US for April to September.

On 2025-04-25, California joined other states in suing the Trump administration over its demand that public schools eliminate diversity, equity, and inclusion initiatives or risk losing federal funding. This follows rulings on 2025-04-24 blocking Trump's threat to cut school funding over DEI.

On 2025-04-25, President Donald Trump pardoned Michele Fiore, a former Las Vegas City Council member. Fiore had been convicted of fraud for allegedly misusing funds intended for a slain police officer memorial for personal expenses.

On 2025-04-25, Donald Trump pardoned Paul Walczak, whose family sought to publicize Ashley Biden’s diary.

On 2025-04-25, the Trump Administration initiated a civil rights inquiry into a dispute over a mascot on Long Island.

On 2025-04-25, the Trump administration, via the Department of Education, launched an investigation into the University of California, Berkeley, focusing on the university's disclosure of foreign funding. Education Secretary Linda McMahon announced that the office of general counsel will investigate UC Berkeley's apparent failure to fully and accurately disclose significant funding received from foreign sources.

On 2025-04-25, President Trump, Rep. Mariannette Miller-Meeks, and former Iowa state Sen. Brad Zaun filed a lawsuit against The Des Moines Register, its parent company Gannett Co., and their former pollster.