On April 1, 2025, Susan Crawford defeated Brad Schimel in the Wisconsin Supreme Court race. This victory secured a 4-3 liberal majority on the court, in a race that cost over $80 million, making it the most expensive judicial election in US history.

On April 2, 2025, a federal judge in California ordered the Trump administration to temporarily restore legal aid to tens of thousands of unaccompanied migrant children. The order will be in effect until April 16, 2025.

On April 1, 2025, California, along with 23 other states and the District of Columbia, sued the Trump administration over cuts to CDC infectious disease funding. The lawsuit, filed in federal court in Rhode Island, seeks to restore the funding, including $972 million for California.

On April 2, 2025, the Trump administration acknowledged in court documents that a Maryland man with protected status was deported to El Salvador. They attributed the deportation to an “administrative error”.

On April 1, 2025, California Assemblymember Bill Essayli was appointed as the U.S. attorney for Los Angeles and surrounding areas by Atty. Gen. Pam Bondi. Trump's firing of an L.A. federal prosecutor on April 1, 2025, is part of a broader war on perceived legal enemies.

Donald Trump is set to announce a new round of sweeping tariffs on April 3, 2025, at the White House, calling it "liberation day." These tariffs may include reciprocal tariffs on US trading partners and 25% tariffs on imports from Mexico and Canada, but are unlikely to alleviate trade uncertainty. Israel will cancel tariffs on U.S. imports ahead of the announcement, while the UK stated it won’t engage in a “kneejerk” response.

On April 1, 2025, the Trump administration began implementing its controversial workforce reduction plan, dismissing thousands of Health and Human Services employees across the country. Fired federal workers protested on Capitol Hill, urging senators to support them, after layoffs commenced at agencies like NIH, FDA, and CDC.

On April 1, 2025, Elon Musk’s cost-cutting team finalized the dismantlement of the US Agency for International Development. This involved ordering the firings of thousands of local workers and US diplomats and civil servants assigned to the agency overseas.

Reported on April 2, 2025, ABC News agreed to a $16 million settlement in favor of Donald Trump in response to his legal challenges.

On April 1, 2025, Retired Lt. Gen. Dan Caine, President Trump's nominee for chairman of the Joint Chiefs of Staff, testified at his confirmation hearing. He vowed to be apolitical and candid.

On April 1, 2025, Willkie Farr & Gallagher, Doug Emhoff's law firm, agreed to provide at least $100 million in pro bono legal work for the Trump administration. The agreement includes combating antisemitism and not engaging in "DEI" efforts, though Emhoff reportedly disagreed with the deal.

On April 2, 2025, Trump demanded that Maine comply with his executive order banning transgender athletes from women’s sports. Governor Mills replied that Maine would follow state and federal law, leading Trump to threaten to cut off all funding to the state, to which Mills responded, “See you in court.”

On April 1, 2025, Republicans won two US House of Representatives seats in Florida. The seats were previously vacated by cabinet appointees, and the Republicans defeated Democratic candidates to win them.

On April 1, 2025, US Senator Cory Booker began a 25-hour and 4-minute speech on the Senate floor, concluding on April 2, 2025. He warned about the dangers of Donald Trump to US democracy, breaking the record previously held by Strom Thurmond.

On April 2, 2025, Texas Attorney General Ken Paxton is considering challenging Senator John Cornyn in the 2026 Republican primary. Internal polling shows Paxton with a significant lead, despite Cornyn's support for gun control legislation following the Uvalde school shooting and Paxton's past impeachment trial and settlement in his criminal indictment.

On April 1, 2025, it was reported that Elon Musk is being sued over signature payments related to a petition in Pennsylvania.

On April 1, 2025, the Los Angeles County Board of Supervisors approved a plan to move hundreds of millions of dollars from the region’s homeless services agency, despite warnings from L.A. Mayor Karen Bass. On April 2, 2025, U.S. District Judge David O. Carter demanded that Mayor Karen Bass and Los Angeles County Board of Supervisors Chairwoman Kathryn Barger fix L.A.'s homelessness system by May.